Acne Fulminans in SAPHO Syndrome
Title: Acne fulminans with synovitis-acne-pustulosis-hyperostosis-osteitis
(SAPHO) syndrome treated with infliximab
Authors: IQbal M, Kolodney MS
Publication: J Am Acad Dermatol. 2005 May;52(5
Suppl 1):S118-20.
Synovitis-acne-pustulosis-hyperostosis-osteitis (SAPHO) syndrome
can cause severe and scarring acne breakouts in the back, chest
and face called acne fulminans. The authors descrive a treatment
of a patient with infliximab, a new monoclonal antibody against
tumor necrosis factor-alpha. They described that after 10 months,
the severe lesions were reduced by 70%, and suggest that infliximab
may be a treatment option for acne fulminans that do not respond
to other treatments.
