Granulysin-derived Peptides for Acne Bacteria
Title: Granulysin-derived peptides demonstrate
antimicrobial and anti-inflammatory effects against Propionibacterium
acnes.
Authors: McInturff JE et al.
Publication: J Invest Dermatol. 2005 Aug;125(2):256-63.
In this study, the authors showed that the granulysin, an enzyme
produced by immune cells, along with a synthetic form of the enzyme,
can kill the acne-causing bacteria Propionium acnes in test tubes.
The synthetic form of granulysin also has increased antibacterial
activity, and may have anti-inflammatory activities. The authors
suggested that synthetic granulysin may be a viable anti-acne
treatment.
