Depression and Suicidal Behavior with Isotretinoin
Title: Depression and suicidal behavior in acne
patients treated with isotretinoin: a systematic review.
Authors: Marqueling AL, Zane LT
Publication: Semin Cutan Med Surg. 2005 Jun;24(2):92-102.
The authors reviewed 9 studies analyzing the possible link of
isotretinoin acne treatment (brand name Accutane) with depression
and suicidal behavior. In these studies, the rates of depression
range from 1% to 11%. The authors found that there is no link
between the two – in fact, they found less cases of depression
in those treated with isotretinoin.