Clobetasol Foam for Psoriasis
Title: Clobetasol propionate foam in the treatment
of psoriasis.
Authors: Reid DC and Kimball AB
Publication: Expert Opin Pharmacother. 2005 Aug;6(10):1735-40.
Psoriasis is a common, chronic skin disorder that commonly affects
the scalp, skin, nails, and joints. Despite treatment, many patients
still suffer from psoriasis, particularly the hard-to-treat form
of scalp-type psoriasis.
The mainstay therapy for moderate-to-severe scalp psoriasis is
topical corticosteroid. However, patients frequently object to
the messiness and poor cosmetic appearance of this form of treatment.
The authors suggested foam-based clobetasol propionate 0.05%
as a treatment, since it has minimal residue and better ease of
application, as compared to traditional forms such as creams,
ointments, and solutions.
Clobetasol propionate 0.05% has been shown to alleviate the symptoms
of several skin diseases, including scalp and body psoriasis,
improved the severity of these diseases, and increase the patient’s
quality of life.
The dose of this medication should be limited to 50 gram per
week, because of the risk of adrenal gland suppression.
