Diet and Psoriasis

Title: Diet and psoriasis: experimental data and clinical evidence.
: Wolters M
Publication: Br J Dermatol. 2005 Oct;153(4):706-14.

While the susceptibility to psoriasis is inherited, the disease is influenced by environmental factors such as infection and stress.

Diet has been suggested to play a role in the development of psoriasis as fasting and eating low-energy diets as well as vegetarian diets improved psoriasis symptoms in some studies. Diet high in N-3 polyunsaturated fatty acids from fish oil has also been shown to be beneficial. All of these diets changed the body’s metabolism of polyunsaturated fatty acid and changed the body’s eicosanoid levels to suppress the body’s inflammatory processes.

Some patients with psoriasis showed elevated sensitivity to gluten, a mixture of plant proteins found predominantly in cereal grains (corn and wheat) that make dough sticky. Gluten has also been used as flour substitute. Patients that eat a gluten-free diet have been shown to have improvement.

Vitamin D, specifically the active form called 1,25-dihydroxyvitamin D(3), which could regulate the immune system has been successfully used as topical treatment of psoriasis.

Editor’s Note: eicosanoid is a group of compounds derived from arachidonic acid. This includes:

  • Leukotrienes
    Lipid compounds that mediate the inflammatory response

  • Prostaglandins
    hormone-like substance involved in blood pressure regulation, smooth musle contraction, and inflammation

  • Thromboxanes.
    A compound derived from prostaglandin that stimulate the aggregation of blood platelets and constriction of the blood vessels.

Main Menu
Health Articles
Health News
Health Research
Site Map

Health Conditions
Cardiovascular Health
Digestive Health
Infectous Diseases
Musculoskeletal Health
Pregnancy & Childbirth
Skin Health

Misc. Health Articles
Presidential Diseases

Medical Research

Psoriasis Overview
Psoriasis Pictures
Research Summaries

©copyright 2004 - Health In Plain English. All Rights Reserved.

Health Articles Health News Health Research Explained in Plain English