Glioblastoma multiforme

Also called spongioblastoma multiforme, this form of brain tumor is the most common form of gliomas. It affects mostly adults (peak age 50 to 60 years) and is twice as common in men.

Glioblastoma multiforme is a highly malignant tumor that grows rapidly and infiltrates the brain extensively. It may become quite large before it is diagnosed.

This form of tumor is usually found in the cerebral hemispheres, particularly the frontal and temporal lobe. It may traverse the corpus callosum to the opposite hemisphere, and can metastasize to infect other tissues of the nervous system through the cerebrospinal fluid.

The symptoms of glioblastoma multiforme include:

  • Increased ICP
  • Nausea
  • Vomiting, particularly in children
  • Headache
  • Papilledema or accumulation of fluid in the optic disc of the eye
  • Changes in vital signs, including increased blood pressure and breathing changes
  • Difficulty in speech
  • Changes in mental ability and behavior, particularly irritability in children
  • Changes in senses

Depending on the location of the tumor, glioblastoma multiforme may also have the following symptoms:

Location Symptoms
Midline Headache that is worse in the morning and made worse by coughing, straining or sudden head movements
Temporal Lobe Seizure
Central region Partial or focal seizure
Optic and oculomotor nerves Visual acuity changes, visual problems
Frontal lobe Changes in reflex and motor responses


See also:
Brain Tumor Overview

Increased intracranial pressure (ICP)

Brain Tumor Types:

Main Menu
Health Articles
Health News
Health Research
Site Map

Health Conditions
Cardiovascular Health
Digestive Health
Infectous Diseases
Musculoskeletal Health
Pregnancy & Childbirth
Skin Health

Misc. Health Articles
Presidential Diseases

All Cancers

Brain Tumor
Breast Cancer
Prostate Cancer

©copyright 2004 - Health In Plain English. All Rights Reserved.

Health Articles Health News Health Research Explained in Plain English